Friday, June 09, 2006

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Bremelanotide at the International Sexologists Conference

A recent article in the German online mag discusses Palatin's presentation of Bremelanotide at a recent International Conference of Sexologists.

The writer follows a researcher who is developing another new drug to enhance sexual arousal and describes what happened when Palatin presented the results of Bremelanotide to the experts in that field.

The article follows George Dodd, a 63 year old Irishman biochemist...

UPDATE: The product associated with George Dodd's research has been made available for purchase as a "Libido Patch" (click for more information).

Before studying biochemistry at Oxford University, Dodd completed a training program as a perfume maker and has now designed a brand new molecule that resembles dopamine - the substance that occurs naturally in the brain and is associated with feelings of pleasure.

His development is meant to "entice the brain into thinking that it's time for sex". But its action on a person is gentle compared to how he later discovered Bremelanotide works...

Dodd's aphrodisiac is an aroma that is supposed to be inhaled repeatedly over a 24-hour period if possible. And another difference between Bremelanotide (or PT-141 as it was originally called) and Dodd's invention is the aroma's relative instability. It "attaches" itself only briefly and gently and then either disintegrates or is discarded.

He attended the International Conference of Sexologists in Lisbon's Marriott Hotel for a four day meeting of the world's leading experts on sex, in part because he was interested in finding out what his competition is up to....

The Bremelanotide presentation by Palatin happened very early in the morning and included Jim Pfaus, the professor of behavioral research at Concordia University in Montreal and tested the drug initial on rats. (Also mentioned in our last article: "Bremelanotide's PT-141 Test Results")

The article states PT-141 "isn't gentle and it isn't intended to merely lightly stimulate the olfactory system. Instead, the spray quickly enters the bloodstream and is ferried directly into the brain."

It also described Bremelanotide as working "alarmingly well" and said the mood in the conference room became very solemn as the fact were presented. The attending endocrinologists, gynecologists, biochemists and the andrologists (and other "ologists") began to realize this new drug may very well be an aphorodisiac that actually works. And may spell the beginnings of a third sexual revolution.

The audience also included a few sex therapists psychologists who apparently asked very critical questions about Bremelanotide - about its social context and the purpose of such a drug.

However the article states the Palatin presenters were very well prepared and promoted the therapeutic benefits. They also claimed it wasn't a "party drug" and that it should be administered as part of a "carefully designed program of psychotherapy"...

At the time of this conference, Bremelanotide had been tested on more than 1,000 human subjects. The neutral, third-party companies used a double-blind, placebo-controlled experiment. And according to Jim Pfaus, 72 percent of the women tested experienced a sensation of general arousal, while 67 percent reported a significant increase in their sexual appetite. (I've read that Viagra is effective with 50% of males, as a comparison)

Research so far has cost Palatin Technologies about $150 million.

Pfaus also mentioned a few unofficial testimonials from an earlier test phase. In that session of tests, older subjects claimed to have had sex several times in a row after using the nasal spray and women raved about sudden attacks of sexual desire.

The subject of this article, George Dodd, was both impressed and perhaps a little disheartened by the impressive results of the Bremelanotide experiments. Especially since his own product would be in direct competition. However he apparently met up with a Palatin Technologies rep or two and they discussed their research amicably.

Although neither of the two products is available to the general public quite yet, there is one other "aphrodisiac" that relies on smell and is available for purchase.

Many of you may have heard or read about Pheromones which, at least in part, is what drives male dogs crazy when nearby female dogs go into "heat" (ready to mate).

Well humans are not so far removed from that process, although our sense of smell is far less than attune compared to dogs, and (perhaps just as importantly) we remove or cover up a lot of our pheromone "scent" as a result of regular washing and wearing clothes.

Personally I wasn't too sure how reliable Pheromone products would be. Do they genuinely work or are they just a waste of money and time...?

But recently I stumbled upon a few tests and studies that ranked one Phermone product as being the top of the line and there's even a University study that proved its effects. Men who tested the Pheromone product actually reported vastly improved incidents of flirting and even "hooking up" compared to the men who were in the placebo group.

The product in question is called Pherlure and their site is chock full of news and magazine reports from where it was tested and verified.

They have links to media coverage from MSNBC, CNN, Time Magazine, WebMD, as well as a link (just a little ways down from the top) from The University of Illinois - Chicago that states "Novel human pheromone formulation (Di-Dehydroepiandrosterone) increases sexual attractiveness."

Pherlure websiteSo while you're waiting for Bremelanotide to be available on your store shelves, you might want to consider doing your own experiment with Pherlure by clicking here. :)

Permanent Link at:
Bremelanotide at the International Sexologists Conference


Anonymous Anonymous said...

I have a question about his chemistry. How does one reach this person?

5:42 PM  
Blogger Editor said...

George Dodd is listed as "Olfactory Researcher" on the following 'Contact Us' page.

Although there is no specific contact information indicated for him, the person listed just below does have extensive contact information listed for Scotland, where Mr George resides afaik.

So getting hold of that individual and/or simply filling out the online form on this webpage may allow you to get a message through to George Dodd so you ask him your questions.

Hope that helps!

~ Bremelanotide Bulletin

10:49 AM  
Blogger David said...

I am very sorry to hear the difficulty that Bremelanotide is having in being aproved for the market .
It sounds to be very effective . I have tried Viagra and Cialis , both with success , also the herbal remedy Libidus and Maxidus .
All three of those ED remedies raise the blood pressure considerably . Viagra and Cialis cause stomach upset and acidity .
I hope Bremelanotide in some form will succeed soon .

1:16 AM  
Blogger Editor said...

Hello David,

Thanks for your comments - you're referring to Palatin Technologies' decision to cease research with Bremelanotide as a treatment for ED and FSAD, as reported in the most recent Bremelanotide Bulletin.

Hopefully their newest Brem-like compound (PL-6983) will get to market quickly and successfully.

Thanks also for your comments about Viagra/Cialis and the herbal options. It seems blood pressure issues aren't confined to just Bremelanotide, and since Viagra *lowers* blood pressure, it seems logical that using Brem (which raised BP in some patients) with it would even things out.

..but then again, maybe the combination would make a person's head implode. ;)

Keep reading this newsletter - or subscribe to the email list or RSS feed - as I hope to report on all the latest drugs in development for arousal disorders.

9:48 AM  

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